Fachartikel 

Einige ausgewählte Publikationen von am NFP 63 beteiligten Forschungsgruppen:


2013

Loss of Prohibitin Induces Mitochondrial Damages Altering β-Cell Function and Survival and Is Responsible for Gradual Diabetes Development.
Supale S, Thorel F, Merkwirth C, Gjinovci A, Herrera PL, Scorrano L, Meda P, Langer T, Maechler P.
Diabetes. 2013 Oct;62(10):3488-99. doi: 10.2337/db13-0152. Epub 2013 Jul 17.

Leptin engages a hypothalamic neurocircuitry to permit survival in the absence of insulin.
Fujikawa T, Berglund ED, Patel VR, Ramadori G, Vianna CR, Vong L, Thorel F, Chera S, Herrera PL, Lowell BB, Elmquist JK, Baldi P, Coppari R.
Cell Metab. 2013 Sep 3;18(3):431-44. doi: 10.1016/j.cmet.2013.08.004.

Molecular diversity subdivides the adult forebrain neural stem cell population.
Giachino C, Basak O, Lugert S, Knuckles P, Obernier K, Fiorelli R, Frank S, Raineteau O, Alvarez-Buylla A, Taylor V.
Stem Cells. 2013 Aug 20. doi: 10.1002/stem.1520. [Epub ahead of print]

TGF-β type II receptor expression in thymic epithelial cells inhibits the development of Hassall's corpuscles in mice.
Odaka C, Hauri-Hohl M, Takizawa K, Nishikawa Y, Yano M, Matsumoto M, Boyd R, Holländer GA.
Int Immunol. 2013 Aug 8. [Epub ahead of print]

PRC1 coordinates timing of sexual differentiation of female primordial
germ cells

Yokobayashi S, Liang C-Y, Kohler H, Nestorov P, Liu Z, Vidal M, van
Lohuizen M, Roloff TC, Peters AHFM. March 2013
Nature, doi:10.1038/nature11918

Molecular determinants of nucleosome retention at CpG-rich sequences in mouse spermatozoa
Erkek S, Hisano M, Liang CY, Gill M, Murr R, Dieker J, Schübeler D, Vlag JV, Stadler MB, Peters AH.
Nat Struct Mol Biol. 2013 Jun 16. doi: 10.1038/nsmb.2599.

An Essential Role for Insulin and IGF1 Receptors in Regulating Sertoli Cell Proliferation, Testis Size, and FSH Action in Mice
Pitetti JL, Calvel P, Zimmermann C, Conne B, Papaioannou MD, Aubry F, Cederroth CR, Urner F, Fumel B, Crausaz M, Docquier M, Herrera PL, Pralong F, Germond M, Guillou F, Jégou B, Nef S.
Mol Endocrinol. 2013 May;27(5):814-27. doi: 10.1210/me.2012-1258. Epub 2013 Mar 21.

IL-7 Produced by Thymic Epithelial Cells Plays a Major Role in the Development of Thymocytes and TCRγδ+ Intraepithelial Lymphocytes
Shitara S, Hara T, Liang B, Wagatsuma K, Zuklys S, Holländer GA, Nakase H, Chiba T, Tani-Ichi S, Ikuta K.
J Immunol. 2013 May 17

Quantitative evaluation of mechanical properties in tissue-engineered auricular cartilage
Nimeskern L, van Osch G Phd, Müller R, Stok K.
Tissue Eng Part B Rev. 2013 May 16

Mechanical evaluation of bacterial nanocellulose as an implant material for ear cartilage replacement
Nimeskern L, Martínez Ávila H, Sundberg J, Gatenholm P, Müller R, Stok KS.
J Mech Behav Biomed Mater. 2013 Jun;22:12-21. doi: 10.1016/j.jmbbm.2013.03.005. Epub 2013 Mar 21.

Small and long non-coding RNAs in cardiac homeostasis and regeneration
Ounzain S, Crippa S, Pedrazzini T.
Biochim Biophys Acta. 2013 Apr;1833(4):923-33. doi: 10.1016/j.bbamcr.2012.08.010. Epub 2012 Aug 23

H3K9/HP1 and Polycomb: Two Key Epigenetic Silencing Pathways for Gene Regulation and Embryo Development
Nestorov P, Tardat M, Peters AH.
Curr Top Dev Biol. 2013;104:243-91. doi: 10.1016/B978-0-12-416027-9.00008-5

A multipotent transit-amplifying neuroblast lineage in the central brain gives rise to optic lobe glial cells in Drosophila
Viktorin G, Riebli N, Reichert H.
Dev Biol. 2013 Apr 27. pii: S0012-1606(13)00200-5. doi: 10.1016/j.ydbio.2013.04.020

A KRAB/KAP1-miRNA cascade regulates erythropoiesis through stage-specific control of mitophagy
Barde I, Rauwel B, Marin-Florez RM, Corsinotti A, Laurenti E, Verp S, Offner S, Marquis J, Kapopoulou A, Vanicek J, Trono D.
Science. 2013 Apr 19;340(6130):350-3. doi: 10.1126/science.1232398. Epub 2013 Mar 14.

2012

Translational Neuroscience: Translating stem cell research to the clinic: A constant crosstalk between basic and applied research
Olivier Raineteau
June 2012, Volume 3, Issue 2, pp 217-221

Bioethica Forum, Focus 3/2012, Blutstammzellspende/Le don de cellules souches du sang/Blood stem cell donation
Jörg Halter, Simone Romagnoli, Bioethica Forum, Focus 3/2012, Volume 5/No. 3/ISSN 1662-6001

3-dimensional examination of the adult mouse subventricular zone reveals lineage-specific microdomains
Azim K, Fiorelli R, Zweifel S, Hurtado-Chong A, Yoshikawa K, Slomianka L, Raineteau O.
PLoS One. 2012;7(11):e49087. doi: 10.1371/journal.pone.0049087. Epub 2012 Nov 15.

The influence of matrix elasticity on chondrocyte behavior in 3D
Schuh E, Hofmann S, Stok KS, Notbohm H, Müller R, Rotter N.
J Tissue Eng Regen Med. 2012 Nov;6(10):e31-42. doi: 10.1002/term.501. Epub 2011 Oct 28.

PPARβ/δ affects pancreatic β cell mass and insulin secretion in mice
Iglesias J, Barg S, Vallois D, Lahiri S, Roger C, Yessoufou A, Pradevand S, McDonald A, Bonal C, Reimann F, Gribble F, Debril MB, Metzger D, Chambon P, Herrera P, Rutter GA, Prentki M, Thorens B, Wahli W.
J Clin Invest. 2012 Nov 1;122(11):4105-17. doi: 10.1172/JCI42127. Epub 2012 Oct 24.

The KRAB-ZFP/KAP1 System Contributes to the Early Embryonic Establishment of Site-Specific DNA Methylation Patterns Maintained during Development
Quenneville S, Turelli P, Bojkowska K, Raclot C, Offner S, Kapopoulou A, Trono D.
Cell Rep. 2012 Oct 25;2(4):766-73. doi: 10.1016/j.celrep.2012.08.043. Epub 2012 Oct 4.

In vivo tumorigenesis was observed after injection of in vitro expanded neural crest stem cells isolated from adult bone marrow
Wislet-Gendebien S, Poulet C, Neirinckx V, Hennuy B, Swingland JT, Laudet E, Sommer L, Shakova O, Bours V, Rogister B.
PLoS One. 2012;7(10):e46425. doi: 10.1371/journal.pone.0046425. Epub 2012 Oct 5.

Characterization and turnover of CD73/IP(3)R3-positive microvillar cells in the adult mouse olfactory epithelium
Pfister S, Dietrich MG, Sidler C, Fritschy JM, Knuesel I, Elsaesser R.
Chem Senses. 2012 Nov;37(9):859-68. doi: 10.1093/chemse/bjs069. Epub 2012 Sep 5.

Small and long non-coding RNAs in cardiac homeostasis and regeneration
Ounzain S, Crippa S, Pedrazzini T.
Biochim Biophys Acta. 2012 Aug 23. [Epub ahead of print]

Embryonic stem cell potency fluctuates with endogenous retrovirus activity
Macfarlan TS, Gifford WD, Driscoll S, Lettieri K, Rowe HM, Bonanomi D, Firth A, Singer O, Trono D, Pfaff SL.
Nature. 2012 Jul 5;487(7405):57-63. doi: 10.1038/nature11244.

Sox10 promotes the formation and maintenance of giant congenital naevi and melanoma
Shakhova O, Zingg D, Schaefer SM, Hari L, Civenni G, Blunschi J, Claudinot S, Okoniewski M, Beermann F, Mihic-Probst D, Moch H, Wegner M, Dummer R, Barrandon Y, Cinelli P, Sommer L.
Nat Cell Biol. 2012 Aug;14(8):882-90. doi: 10.1038/ncb2535. Epub 2012 Jul 8.

Analysis of neural stem cell self-renewal and differentiation by transgenic RNAi in Drosophila
Jiang Y, Reichert H.
Arch Biochem Biophys. 2012 Aug 13. [Epub ahead of print]

FACS Purification and Transcriptome Analysis of Drosophila Neural Stem Cells Reveals a Role for Klumpfuss in Self-Renewal
Berger C, Harzer H, Burkard TR, Steinmann J, van der Horst S, Laurenson AS, Novatchkova M, Reichert H, Knoblich JA.
Cell Rep. 2012 Aug 7. [Epub ahead of print]

KAP1 regulates gene networks controlling T-cell development and responsiveness
Santoni de Sio FR, Barde I, Offner S, Kapopoulou A, Corsinotti A, Bojkowska K, Genolet R, Thomas JH, Luescher IF, Pinschewer D, Harris N, Trono D.
FASEB J. 2012 Aug 7. [Epub ahead of print]

Liver-specific ablation of KRAB associated protein 1 in mice leads to male-predominant hepatosteatosis and development of liver adenoma
Bojkowska K, Aloisio F, Cassano M, Kapopoulou A, de Sio FS, Zangger N, Offner S, Cartoni C, Thomas C, Quenneville S, Johnsson K, Trono D.
Hepatology. 2012 Jun 8. doi: 10.1002/hep.25767. [Epub ahead of print]

Parental epigenetic control of embryogenesis: a balance between inheritance and reprogramming?
Gill ME, Erkek S, Peters AH.
Curr Opin Cell Biol. 2012 Jun;24(3):387-96. Epub 2012 Mar 23.

Temporal control of neural crest lineage generation by Wnt/β-catenin signaling
Hari L, Miescher I, Shakhova O, Suter U, Chin L, Taketo M, Richardson WD, Kessaris N, Sommer L.
Development. 2012 Jun;139(12):2107-17. Epub 2012 May 9.

Neural stem cells in Drosophila: molecular genetic mechanisms underlying normal neural proliferation and abnormal brain tumor formation
Saini N, Reichert H.
Stem Cells Int. 2012;2012:486169. Epub 2012 Jun 7.
http://www.ncbi.nlm.nih.gov/pubmed/22737173

Polycomb function during oogenesis is required for mouse embryonic development
Posfai E, Kunzmann R, Brochard V, Salvaing J, Cabuy E, Roloff TC, Liu Z, Tardat M, van Lohuizen M, Vidal M, Beaujean N, Peters AH.
Genes Dev. 2012 May 1;26(9):920-32. Epub 2012 Apr 12.

Early Decline in Progenitor Diversity in the Marmoset Lateral Ventricle
Azim K, Zweifel S, Klaus F, Yoshikawa K, Amrein I, Raineteau O.
Cereb Cortex. 2012 Apr 3. [Epub ahead of print]

KAP1 regulates gene networks controlling mouse B lymphoid cell differentiation and function
Santoni de Sio FR, Massacand J, Barde I, Offner S, Corsinotti A, Kapopoulou A, Bojkowska K, Dagklis A, Fernandez M, Ghia P, Thomas JH, Pinschewer D, Harris N, Trono D.
Blood. 2012 Apr 3. [Epub ahead of print]

Neural crest progenitors and stem cells: From early development to adulthood
Dupin E, Sommer L.
Dev Biol. 2012 Mar 8. [Epub ahead of print]

Future trends in hematopoietic stem cell transplantation
Halter J, Passweg J, Häusermann P.
Curr Probl Dermatol. 2012;43:165-70. Epub 2012 Feb 17. Review.

Isolation of cardiovascular precursor cells from the human fetal heart
Gonzales C, Ullrich ND, Gerber S, Berthonneche C, Niggli E, Pedrazzini T.
Tissue Eng Part A. 2012 Jan;18(1-2):198-207. Epub 2011 Sep 27.

Programmed cell death in type II neuroblast lineages is required for central complex development in the Drosophila brain
Jiang Y, Reichert H.
Neural Dev. 2012 Jan 18;7:3.

Chondrocyte redifferentiation in 3D: the effect of adhesion site density and
substrate elasticity
Schuh E, Hofmann S, Stok K, Notbohm H, Müller R, Rotter N.
Biomed Mater Res A. 2012 Jan;100(1):38-47, doi: 10.1002/jbm.a.33226.

2011

Multimodal image coregistration and inducible selective cell ablation to evaluate imaging ligands
Virostko J, Henske J, Vinet L, Lamprianou S, Dai C, Radhika A, Baldwin RM, Ansari MS, Hefti F, Skovronsky D, Kung HF, Herrera PL, Peterson TE, Meda P, Powers AC.
Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):20719-24. Epub 2011 Dec 5.

Normal glucagon signaling and β-cell function after near-total α-cell ablation
in adult mice
Thorel F, Damond N, Chera S, Wiederkehr A, Thorens B, Meda P, Wollheim CB, Herrera PL.
Diabetes. 2011 Nov;60(11):2872-82. Epub 2011 Sep 16.

Transgenic overexpression of the transcription factor Nkx6.1 in β-cells of mice
does not increase β-cell proliferation, β-cell mass, or improve glucose
clearance
Schaffer AE, Yang AJ, Thorel F, Herrera PL, Sander M.
Mol Endocrinol. 2011 Nov;25(11):1904-14, doi: 10.1210/me.2011-1139. Epub 2011 Sep 29.

In embryonic stem cells, ZFP57/KAP1 recognize a methylated hexanucleotide to
affect chromatin and DNA methylation of imprinting control regions
Quenneville S, Verde G, Corsinotti A, Kapopoulou A, Jakobsson J, Offner S, Baglivo I, Pedone PV, Grimaldi G, Riccio A, Trono D.
Mol Cell. 2011 Nov 4;44(3):361-72.

The influence of matrix elasticity on chondrocyte behavior in 3D
Schuh E, Hofmann S, Stok KS, Notbohm H, Müller R, Rotter N.
J Tissue Eng Regen Med. 2011 Oct 28, doi: 10.1002/term.501.

Considérations éthiques et juridiques sur les modalités du don dans la transplantation
Romagnoli S, Bart T, Buerkli P, Halter J.
Jusletter 29. August 2011, ISSN 1424-7410.

Multipotent neural stem cells generate glial cells of the central complex
through transit amplifying intermediate progenitors in Drosophila brain
development
Viktorin G, Riebli N, Popkova A, Giangrande A, Reichert H.
Dev Biol. 2011 Aug 15;356(2):553-65, Epub 2011 Jun 25.

Epigenetics: Tet proteins in the limelight
Véron N, Peters AH.
Nature 473, 293–294, DOI:doi:10.1038/473293a, Published online 18 May 2011.

In vivo conditional Pax4 overexpression in mature islet β-cells prevents stress-induced hyperglycemia in mice
Hu He KH, Lorenzo PI, Brun T, Jimenez Moreno CM, Aeberhard D, Vallejo Ortega J, Cornu M, Thorel F, Gjinovci A, Thorens B, Herrera PL, Meda P, Wollheim CB, Gauthier BR.
Diabetes, 2011 Jun; 60(6):1705-15, Epub 2011 Apr 26.

Targeted electroporation of defined lateral ventricular walls: a novel and rapid method to study fate specification during postnatal forebrain neurogenesis
Fernández ME, Croce S, Boutin C, Cremer H, Raineteau O.
Neural Dev, 2011 Apr 5;6:13.

Sequential generation of olfactory bulb glutamatergic neurons by Neurog2-expressing precursor cells
Winpenny E, Lebel-Potter M, Fernandez ME, Brill MS, Götz M, Guillemot F, Raineteau O.
Neural Dev, 2011 Apr 5;6:12.

Thymic T-cell development in allogeneic stem cell transplantation

Krenger W, Blazar BR, Holländer GA.
Blood, 2011 Jun 23; 117(25):6768-76, Epub 2011 Mar 22.

A gene-rich, transcriptionally active environment and the pre-deposition of repressive marks are predictive of susceptibility to KRAB/KAP1-mediated silencing
Meylan S, Groner A, Ambrosini G, Malani N, Quenneville S, Zangger N, Kapopoulou A, Kauzlaric A, Rougemont J, Ciuffi A, Bushman F, Bucher P, Trono D.
Gnomics (ISSN: 1471-2164), vol. 12, num. 1, p. 378.

Current developments in the use of stem cell for therapeutic neovascularisation: is the future therapy «cell free»?
Yang Z, Di Santo S, Kalka C.
Swiss Med Wkly 2011 Jan, Vol 141, p. 18-23.

2010

The role of the thymus in allogeneic hematopoietic stem cell transplantation.
Krenger W, Holländer GA.
Swiss Med Wkly, 2010 Jul 19;140:w13051. doi: 10.4414/smw.2010.13051.

Inducible Gene and shRNA Expression in Resident Hematopoietic Stem Cells In Vivo.
Laurenti E, Barde I, Verp S, Offner S, Wilson A, Quenneville S, Wiznerowicz M, McDonald HR, Trono D, Trumpp A.
Stem Cells. 2010 Jul 16.

Repressive and active histone methylation mark distinct promoters in human and mouse spermatozoa.
Brykczynska U, Hisano M, Erkek S, Ramos L, Oakeley EJ, Roloff TC, Beisel C, Schübeler D, Stadler MB, Peters AH.
Nat Struct Mol Biol, 2010 Jun;17(6):679-87, Epub 2010 May 16.

Neural crest-derived stem cells.
Shakhova O, Sommer L.
StemBook, Cambridge (MA): Harvard Stem Cell Institute; 2008-2010 May 4.

Conversion of adult pancreatic alpha-cells to beta-cells after extreme beta-cell loss.
Thorel F, Népote V, Avril I, Kohno K, Desgraz R, Chera S, Herrera PL.
Nature, 2010 Apr 22;464(7292):1149-54. Epub 2010 Apr 4.

KRAB-zinc finger proteins and KAP1 can mediate long-range transcriptional repression through heterochromatin spreading.
Groner AC, Meylan S, Ciuffi A, Zangger N, Ambrosini G, Dénervaud N, Bucher P, Trono D.
PLoS Genet, 2010 Mar 5;6(3):e1000869.

© SNF 2014 | Wildhainweg 3, Postfach 8232, 3001 Bern | Tel. +41 31 308 22 22 | Impressum | Seite drucken | Seite weiterempfehlen Link zur Website der Stiftung "Zugang für alle" SNFWEB07