Selected publications of participating research groups:
2012
Chondrocyte redifferentiation in 3D: the effect of adhesion site density and
substrate elasticity
Schuh E, Hofmann S, Stok K, Notbohm H, Müller R, Rotter N.
J Biomed Mater Res A. 2012 Jan;100(1):38-47, doi: 10.1002/jbm.a.33226.
2011
Normal glucagon signaling and β-cell function after near-total α-cell ablation
in adult mice
Thorel F, Damond N, Chera S, Wiederkehr A, Thorens B, Meda P, Wollheim CB, Herrera PL.
Diabetes. 2011 Nov;60(11):2872-82. Epub 2011 Sep 16.
Transgenic overexpression of the transcription factor Nkx6.1 in β-cells of mice
does not increase β-cell proliferation, β-cell mass, or improve glucose
clearance
Schaffer AE, Yang AJ, Thorel F, Herrera PL, Sander M.
Mol Endocrinol. 2011 Nov;25(11):1904-14, doi: 10.1210/me.2011-1139. Epub 2011 Sep 29.
In embryonic stem cells, ZFP57/KAP1 recognize a methylated hexanucleotide to
affect chromatin and DNA methylation of imprinting control regions
Quenneville S, Verde G, Corsinotti A, Kapopoulou A, Jakobsson J, Offner S, Baglivo I, Pedone PV, Grimaldi G, Riccio A, Trono D.
Mol Cell. 2011 Nov 4;44(3):361-72.
The influence of matrix elasticity on chondrocyte behavior in 3D
Schuh E, Hofmann S, Stok KS, Notbohm H, Müller R, Rotter N.
J Tissue Eng Regen Med. 2011 Oct 28, doi: 10.1002/term.501.
Considérations éthiques et juridiques sur les modalités du don dans la transplantation
Romagnoli S, Bart T, Buerkli P, Halter J.
Jusletter 29. August 2011, ISSN 1424-7410.
Multipotent neural stem cells generate glial cells of the central complex
through transit amplifying intermediate progenitors in Drosophila brain
development
Viktorin G, Riebli N, Popkova A, Giangrande A, Reichert H.
Dev Biol. 2011 Aug 15;356(2):553-65, Epub 2011 Jun 25.
Epigenetics: Tet proteins in the limelight
Véron N, Peters AH.
Nature 473, 293–294, DOI:doi:10.1038/473293a, Published online 18 May 2011.
In vivo conditional Pax4 overexpression in mature islet β-cells prevents stress-induced hyperglycemia in mice
Hu He KH, Lorenzo PI, Brun T, Jimenez Moreno CM, Aeberhard D, Vallejo Ortega J, Cornu M, Thorel F, Gjinovci A, Thorens B, Herrera PL, Meda P, Wollheim CB, Gauthier BR.
Diabetes, 2011 Jun; 60(6):1705-15, Epub 2011 Apr 26.
Targeted electroporation of defined lateral ventricular walls: a novel and rapid method to study fate specification during postnatal forebrain neurogenesis
Fernández ME, Croce S, Boutin C, Cremer H, Raineteau O.
Neural Dev, 2011 Apr 5;6:13.
Sequential generation of olfactory bulb glutamatergic neurons by Neurog2-expressing precursor cells
Winpenny E, Lebel-Potter M, Fernandez ME, Brill MS, Götz M, Guillemot F, Raineteau O.
Neural Dev, 2011 Apr 5;6:12.
Thymic T-cell development in allogeneic stem cell transplantation
Krenger W, Blazar BR, Holländer GA.
Blood, 2011 Jun 23; 117(25):6768-76, Epub 2011 Mar 22.
A gene-rich, transcriptionally active environment and the pre-deposition of repressive marks are predictive of susceptibility to KRAB/KAP1-mediated silencing
Meylan S, Groner A, Ambrosini G, Malani N, Quenneville S, Zangger N, Kapopoulou A, Kauzlaric A, Rougemont J, Ciuffi A, Bushman F, Bucher P, Trono D.
Gnomics (ISSN: 1471-2164), vol. 12, num. 1, p. 378.
Current developments in the use of stem cell for therapeutic neovascularisation: is the future therapy «cell free»?
Yang Z, Di Santo S, Kalka C.
Swiss Med Wkly 2011 Jan, Vol 141, p. 18-23.
2010
The role of the thymus in allogeneic hematopoietic stem cell transplantation.
Krenger W, Holländer GA.
Swiss Med Wkly. 2010 Jul 19;140:w13051. doi: 10.4414/smw.2010.13051.
Inducible Gene and shRNA Expression in Resident Hematopoietic Stem Cells In Vivo.
Laurenti E, Barde I, Verp S, Offner S, Wilson A, Quenneville S, Wiznerowicz M, McDonald HR, Trono D, Trumpp A.
Stem Cells. 2010 Jul 16.
Repressive and active histone methylation mark distinct promoters in human and mouse spermatozoa.
Brykczynska U, Hisano M, Erkek S, Ramos L, Oakeley EJ, Roloff TC, Beisel C, Schübeler D, Stadler MB, Peters AH.
Nat Struct Mol Biol, 2010 Jun;17(6):679-87, Epub 2010 May 16.
Neural crest-derived stem cells.
Shakhova O, Sommer L.
StemBook, Cambridge (MA): Harvard Stem Cell Institute; 2008-2010 May 4.
Conversion of adult pancreatic alpha-cells to beta-cells after extreme beta-cell loss.
Thorel F, Népote V, Avril I, Kohno K, Desgraz R, Chera S, Herrera PL.
Nature, 2010 Apr 22;464(7292):1149-54. Epub 2010 Apr 4.
KRAB-zinc finger proteins and KAP1 can mediate long-range transcriptional repression through heterochromatin spreading.
Groner AC, Meylan S, Ciuffi A, Zangger N, Ambrosini G, Dénervaud N, Bucher P, Trono D.
PLoS Genet, 2010 Mar 5;6(3):e1000869.